Deep Eutectic Solvents for the Extraction of Bioactive Compounds from Natural Sources and Agricultural By-Products

In this work, a review about the applicability of eutectic solvents, mainly deep solvents (DES) and natural (NADES), for extraction bioactive compounds from products has been carried out. These alternative have shown not only to high yields but also be environmentally friendly, exhibiting very low or almost no toxicity, compared conventional organic solvents. The last trends main methods that most widely used in studies using these emerging reviewed, as well varied sources which they used, including agro-food by-products. Besides biodegradability is reviewed. Likewise, different reported bioactivity tests included, extracts obtained with ecological tested antioxidant activity analysis vivo rats, through vitro cytotoxicity tests.